BDBM50333028 3-(Pyridin-3-ylethynyl)-1H-indazole::CHEMBL1631891

SMILES c1ccc2c(n[nH]c2c1)C#Cc1cccnc1

InChI Key InChIKey=GZOXBNAYOLYVTR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333028   

LigandPNGBDBM50333028(3-(Pyridin-3-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of mTORC1 expressed in HEK293 cells assessed as PRAS40 Ser183 phosphorylation level by LanthaScreen cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333028(3-(Pyridin-3-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of PI3Kalpha by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333028(3-(Pyridin-3-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mTOR by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50333028(3-(Pyridin-3-ylethynyl)-1H-indazole | CHEMBL163189...)
Affinity DataIC50:  2.08E+4nMAssay Description:Inhibition of PDK1 by Z'-LYTE kinase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed