BDBM50333448 3-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)pyrrolidine::CHEMBL1645615

SMILES Fc1cccc(Oc2c(F)cccc2Cl)c1OC1CCNC1

InChI Key InChIKey=PDVOMSJUMYNNBT-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50333448   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333448(3-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)py...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333448(3-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)py...)
Affinity DataKi:  226nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333448(3-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)py...)
Affinity DataKi: >4.90E+3nMAssay Description:Displacement of [3H]citalopram from human SERT by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333448(3-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)py...)
Affinity DataKi: >6.46E+3nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333448(3-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)py...)
Affinity DataEC50:  97nMAssay Description:Agonist activity at human cloned NET expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed