BDBM50334728 CHEMBL1642862::N-{[3-(1-Naphthylsulfonyl)-1H-indazol-5yl]methyl}ethane-1,2-diamine HCl

SMILES NCCNCc1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=FNEPLPAYLVDBNM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334728   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334728(CHEMBL1642862 | N-{[3-(1-Naphthylsulfonyl)-1H-inda...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334728(CHEMBL1642862 | N-{[3-(1-Naphthylsulfonyl)-1H-inda...)
Affinity DataIC50:  156nMAssay Description:Antagonist activity at cloned human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed