BDBM50335449 1-(4-(5-cyclohexylbenzofuran-2-yl)benzyl)azetidine-3-carboxylic acid::CHEMBL1651703

SMILES OC(=O)C1CN(Cc2ccc(cc2)-c2cc3cc(ccc3o2)C2CCCCC2)C1

InChI Key InChIKey=HGHYQVXLKNDCDC-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50335449   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335449(1-(4-(5-cyclohexylbenzofuran-2-yl)benzyl)azetidine...)
Affinity DataEC50:  600nMAssay Description:Agonist activity at human S1P1R expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335449(1-(4-(5-cyclohexylbenzofuran-2-yl)benzyl)azetidine...)
Affinity DataEC50:  460nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335449(1-(4-(5-cyclohexylbenzofuran-2-yl)benzyl)azetidine...)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed