BDBM50335459 1-(4-(5-butoxybenzofuran-2-yl)-3-methoxybenzyl)azetidine-3-carboxylic acid::CHEMBL1651713

SMILES CCCCOc1ccc2oc(cc2c1)-c1ccc(CN2CC(C2)C(O)=O)cc1OC

InChI Key InChIKey=BFJBNYIYUUPKMY-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50335459   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335459(1-(4-(5-butoxybenzofuran-2-yl)-3-methoxybenzyl)aze...)
Affinity DataEC50:  420nMAssay Description:Agonist activity at human S1P1R expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335459(1-(4-(5-butoxybenzofuran-2-yl)-3-methoxybenzyl)aze...)
Affinity DataEC50:  653nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335459(1-(4-(5-butoxybenzofuran-2-yl)-3-methoxybenzyl)aze...)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed