BDBM50335784 2-[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethyl]-4-fluorobenzonitrile::CHEMBL1650443
SMILES Cn1c(=O)cc(N2CCC[C@@H](N)C2)n(Cc2cc(F)ccc2C#N)c1=O
InChI Key InChIKey=IWYJYHUNXVAVAA-OAHLLOKOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50335784
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured for 5 to 10 minsMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The First Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant DPP4 using Gly-Pro-7-amido-4-methyl-coumarin as substrate incubated for 15 mins by fluorescence assayMore data for this Ligand-Target Pair