BDBM50336889 (2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]-3-(4-{[1-(trifluoromethyl)cyclopropyl]methyl}-1H-imidazol-2-yl)propan-2-ol::CHEMBL1672354
SMILES O[C@@](Cc1ncc(CC2(CC2)C(F)(F)F)[nH]1)(c1ccc(cc1)-n1cccn1)C(F)(F)F
InChI Key InChIKey=UJINBEQCDMOAHM-SFHVURJKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50336889
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]Bag-3 from rat BRS-3More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]Bag-3 from rat BRS-3More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]Bag-3 from mouse BRS-3More data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]-Bombesin (6-14) from human BRS-3More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: >8.00E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Displacement of [3H]Bag-3 from mouse BRS-3More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Agonist activity at human BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence ...More data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Agonist activity at mouse BRS3 expressed in CHO-K1 cells by IP-One HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.20nMAssay Description:Agonist activity at rat BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence as...More data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Agonist activity at mouse BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence ...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Agonist activity at human BRS3 expressed in CHO-K1 cells by IP-One HTRF assayMore data for this Ligand-Target Pair