BDBM50337024 2-(difluoromethyl)-5-(3-(1-methylcyclopropyl)propyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione::CHEMBL1672639

SMILES CC1(CCCc2cc(=O)oc3nc([nH]c(=O)c23)C(F)F)CC1

InChI Key InChIKey=BRWOJXBDKLPQCT-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50337024   

TargetHydroxycarboxylic acid receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337024(2-(difluoromethyl)-5-(3-(1-methylcyclopropyl)propy...)
Affinity DataEC50:  1.12E+3nMAssay Description:Agonist activity at human GPR109bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50337024(2-(difluoromethyl)-5-(3-(1-methylcyclopropyl)propy...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50337024(2-(difluoromethyl)-5-(3-(1-methylcyclopropyl)propy...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at mouse GPR109aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337024(2-(difluoromethyl)-5-(3-(1-methylcyclopropyl)propy...)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed