BDBM50337494 5-(phenylethynyl)isoindoline-1,3-dione::CHEMBL1682790

SMILES O=C1NC(=O)c2cc(ccc12)C#Cc1ccccc1

InChI Key InChIKey=RTUKPSOCDCOAMX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337494   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt Medical Center

Curated by ChEMBL
LigandPNGBDBM50337494(5-(phenylethynyl)isoindoline-1,3-dione | CHEMBL168...)
Affinity DataEC50:  5.90nMAssay Description:Positive allosteric modulation of mGlu5 receptor assessed as calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt Medical Center

Curated by ChEMBL
LigandPNGBDBM50337494(5-(phenylethynyl)isoindoline-1,3-dione | CHEMBL168...)
Affinity DataEC50:  11nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in human HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed