BDBM50337844 1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)-4-methylpiperazine::CHEMBL1683880::US10562878, Compound 112

SMILES CN1CCN(CC2(CCCCC2)c2ccc(Cl)c(Cl)c2)CC1

InChI Key InChIKey=FSYUMFOIUHBSHI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50337844   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337844(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)-4-met...)
Affinity DataIC50:  39nMAssay Description:Inhibition of human recombinant Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337844(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)-4-met...)
Affinity DataIC50:  299nMAssay Description:Inhibition of human recombinant serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337844(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)-4-met...)
Affinity DataIC50: <1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337844(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)-4-met...)
Affinity DataIC50:  39nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337844(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)-4-met...)
Affinity DataIC50:  299nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails US Patent