BDBM50339376 (+/-)-3-(4-Chlorophenyl)-3-(1-hydroxymethylcyclopropylmethoxy)-2-(4-iodobenzyl)-2,3-dihydroisoindol-1-one::CHEMBL1688281

SMILES OCC1(COC2(N(Cc3ccc(I)cc3)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1

InChI Key InChIKey=UUMATCHVJQJMCG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339376   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339376((+/-)-3-(4-Chlorophenyl)-3-(1-hydroxymethylcyclopr...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed