BDBM50339380 (+/-)-3-(4-Chlorophenyl)-2-((S)-1-(4-chlorophenyl)ethyl)-3-((1-(hydroxymethyl)cyclopropyl)methoxy)isoindolin-1-one::CHEMBL1688285::US8618158, NU8419

SMILES C[C@H](N1C(=O)c2ccccc2C1(OCC1(CO)CC1)c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=IYUMLCRMDKLSQE-HSYKDVHTSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339380   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339380((+/-)-3-(4-Chlorophenyl)-2-((S)-1-(4-chlorophenyl)...)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339380((+/-)-3-(4-Chlorophenyl)-2-((S)-1-(4-chlorophenyl)...)
Affinity DataIC50:  8.90E+3nMT: 2°CAssay Description:Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...More data for this Ligand-Target Pair
In DepthDetails US Patent