BDBM50339607 1-Hydroxy-6-phenyl-4-trifluoromethyl-1H-indole-2-carboxylic Acid::CHEMBL1688790::LDHA Inhibitor, 4
SMILES OC(=O)c1cc2c(cc(cc2n1O)-c1ccccc1)C(F)(F)F
InChI Key InChIKey=KGXDBNBXAPVUIM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50339607
Affinity DataKi: 4.70E+3nMAssay Description:Competitive inhibition of human LDH-A using pyruvate as substrate after 5 mins by calorimetric assay relative to controlMore data for this Ligand-Target Pair
Affinity DataKi: 8.90E+3nMAssay Description:Competitive inhibition of human LDH-A using NADH as substrate after 5 mins by calorimetric assay relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMpH: 7.5 T: 2°CAssay Description:Enzyme assay using lactate dehydrogenase A (LDHA).More data for this Ligand-Target Pair
Affinity DataKd: 9.00E+3nMpH: 7.5 T: 2°CAssay Description:NMR spectra were acquired on Bruker Avance 600 MHz spectrometers at 298 K using a 5 mm triple-resonance HCN cryoprobe. Ligand binding was detected u...More data for this Ligand-Target Pair