BDBM50339685 4-(Thiophen-3-yl)-N-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)benzamide oxalic acid salt::CHEMBL1689006

SMILES FCCOc1ccccc1N1CCN(CCCCNC(=O)c2ccc(cc2)-c2ccsc2)CC1

InChI Key InChIKey=TVWNOPFEOFGKFJ-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50339685   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50339685(4-(Thiophen-3-yl)-N-(4-(4-(2-(2-fluoroethoxy)pheny...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [125I]-IABN from human D3 receptor transfected in human HEK 293 cells by gamma-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Temple University School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50339685(4-(Thiophen-3-yl)-N-(4-(4-(2-(2-fluoroethoxy)pheny...)
Affinity DataKi:  0.170nMAssay Description:Displacement of 2,3-dimethoxy-5-[125I]-iodo-N-[9-benzyl-9-azabicyclo[3.3.1]nonan-3beta-yl]benzamide from human dopamine D2L receptor expressed in HEK...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Temple University School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50339685(4-(Thiophen-3-yl)-N-(4-(4-(2-(2-fluoroethoxy)pheny...)
Affinity DataKi:  27.7nMAssay Description:Displacement of [125I]-IABN from human D2 receptor transfected in human HEK 293 cells by gamma-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50339685(4-(Thiophen-3-yl)-N-(4-(4-(2-(2-fluoroethoxy)pheny...)
Affinity DataKi:  28nMAssay Description:Displacement of 2,3-dimethoxy-5-[125I]-iodo-N-[9-benzyl-9-azabicyclo[3.3.1]nonan-3beta-yl]benzamide from human dopamine D3 receptor expressed in HEK2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50339685(4-(Thiophen-3-yl)-N-(4-(4-(2-(2-fluoroethoxy)pheny...)
Affinity DataKi:  246nMAssay Description:Binding affinity to human D4 receptor transfected in human HEK293 cells by gamma-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAP-2 complex subunit sigma(RAT)
Washington University

Curated by ChEMBL
LigandPNGBDBM50339685(4-(Thiophen-3-yl)-N-(4-(4-(2-(2-fluoroethoxy)pheny...)
Affinity DataKi:  5.96E+3nMAssay Description:Displacement of [3H]-DTG from rat sigma2 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Washington University

Curated by ChEMBL
LigandPNGBDBM50339685(4-(Thiophen-3-yl)-N-(4-(4-(2-(2-fluoroethoxy)pheny...)
Affinity DataKi:  2.09E+4nMAssay Description:Displacement of [3H]-pentazocine from guinea pig sigma1 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed