BDBM50339808 CHEMBL1689279::N-[(5aR,7aR,7bS,9aS,12S,13aR,15aR,15bS)-2,3,4,5,5a,6,7,7a,7b,8,9,9a,10,11,12,13,13a,15,15a,15b-Eicosahydro-5,5,7a,7b,9a,12,15b-heptamethyl-3,15-dioxo-1H-chryseno[2,1-c]azepine-12-yl]urea
SMILES C[C@@]1(CC[C@]2(C)CC[C@]3(C)C(=CC(=O)[C@@H]4[C@@]5(C)CCC(=O)NC(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)NC(N)=O
InChI Key InChIKey=OXEJYJIHFPSCHI-LPXJIFNVSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50339808
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology
Curated by ChEMBL
University Of Technology
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Technology
Curated by ChEMBL
University Of Technology
Curated by ChEMBL
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-[3H]cortisone to cortisol after 10 mins by scint...More data for this Ligand-Target Pair