BDBM50339811 (3beta,18beta,20beta)-N-Hydroxy-N-methyl-[3-(1,2,4-oxadiazole-5(2H)-one)]-11-oxo-olean-12-en-29-amide::CHEMBL1689282
SMILES CN(O)C(=O)[C@@]1(C)CC[C@]2(C)CC[C@]3(C)C(=CC(=O)[C@@H]4[C@@]5(C)CC[C@H](Oc6nc(=O)o[nH]6)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1
InChI Key InChIKey=ZBWAJSRMNVFHIR-OAFQVGTHSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50339811
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology
Curated by ChEMBL
University Of Technology
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Technology
Curated by ChEMBL
University Of Technology
Curated by ChEMBL
Affinity DataIC50: 504nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-[3H]cortisone to cortisol after 10 mins by scint...More data for this Ligand-Target Pair