BDBM50340001 CHEMBL1762478::rac-4-chloro-2-(1-(methylamino)pentan-3-yloxy)benzonitrile hydrochloride

SMILES CCC(CCNC)Oc1cc(Cl)ccc1C#N

InChI Key InChIKey=VJGKGXRSJKSLFP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50340001   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Astrazeneca Charnwood

Curated by ChEMBL
LigandPNGBDBM50340001(CHEMBL1762478 | rac-4-chloro-2-(1-(methylamino)pen...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Astrazeneca Charnwood

Curated by ChEMBL
LigandPNGBDBM50340001(CHEMBL1762478 | rac-4-chloro-2-(1-(methylamino)pen...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca Charnwood

Curated by ChEMBL
LigandPNGBDBM50340001(CHEMBL1762478 | rac-4-chloro-2-(1-(methylamino)pen...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human recombinant iNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca Charnwood

Curated by ChEMBL
LigandPNGBDBM50340001(CHEMBL1762478 | rac-4-chloro-2-(1-(methylamino)pen...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of iNOS in intact human DLD1 cells assessed as nitric oxide productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Astrazeneca Charnwood

Curated by ChEMBL
LigandPNGBDBM50340001(CHEMBL1762478 | rac-4-chloro-2-(1-(methylamino)pen...)
Affinity DataIC50:  400nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed