BDBM50341494 CHEMBL1765464::N-(5-(3-(5-Methyl-1,2,4-oxadiazol-3-yl)imidazo[1,2-a]pyridin-6-yl)pyridin-3-yl)benzenesulfonamide

SMILES Cc1nc(no1)-c1cnc2ccc(cn12)-c1cncc(NS(=O)(=O)c2ccccc2)c1

InChI Key InChIKey=OLKGECFEMGIHJD-UHFFFAOYSA-N

Data  1 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50341494   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341494(CHEMBL1765464 | N-(5-(3-(5-Methyl-1,2,4-oxadiazol-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of PI3Kalpha after 180 mins by luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 19(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341494(CHEMBL1765464 | N-(5-(3-(5-Methyl-1,2,4-oxadiazol-...)
Affinity DataKd:  88nMAssay Description:Binding affinity to CDK11 by high-throughput binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341494(CHEMBL1765464 | N-(5-(3-(5-Methyl-1,2,4-oxadiazol-...)
Affinity DataKd:  25nMAssay Description:Binding affinity to PIK3CB by high-throughput binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341494(CHEMBL1765464 | N-(5-(3-(5-Methyl-1,2,4-oxadiazol-...)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to PIK3CA by high-throughput binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Korea Advanced Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50341494(CHEMBL1765464 | N-(5-(3-(5-Methyl-1,2,4-oxadiazol-...)
Affinity DataKd:  39nMAssay Description:Binding affinity to mTOR by high-throughput binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed