BDBM50342563 (E)-5-chloro-3-(2-oxopropylidene)indolin-2-one::CHEMBL1770395

SMILES CC(=O)C=C1C(=O)Nc2ccc(Cl)cc12

InChI Key InChIKey=NGBDRYCUEWUGNM-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50342563   

TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342563((E)-5-chloro-3-(2-oxopropylidene)indolin-2-one | C...)
Affinity DataKi:  900nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342563((E)-5-chloro-3-(2-oxopropylidene)indolin-2-one | C...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342563((E)-5-chloro-3-(2-oxopropylidene)indolin-2-one | C...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed