BDBM50342567 (E)-4-chloro-1-methyl-3-(2-oxo-2-(pyridin-3-yl)ethylidene)indolin-2-one::CHEMBL1770526

SMILES CN1C(=O)\C(=C\C(=O)c2cccnc2)c2c1cccc2Cl

InChI Key InChIKey=UMAYJRZPQAAORG-DHZHZOJOSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50342567   

TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342567((E)-4-chloro-1-methyl-3-(2-oxo-2-(pyridin-3-yl)eth...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342567((E)-4-chloro-1-methyl-3-(2-oxo-2-(pyridin-3-yl)eth...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342567((E)-4-chloro-1-methyl-3-(2-oxo-2-(pyridin-3-yl)eth...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed