BDBM50342583 (E)-4-chloro-3-(2-(2-methoxyphenyl)-2-oxoethylidene)indolin-2-one::CHEMBL1770521
SMILES COc1ccccc1C(=O)\C=C1\C(=O)Nc2cccc(Cl)c12
InChI Key InChIKey=ULAXMAMZNHGQMV-PKNBQFBNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50342583
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataKi: 3.30E+3nMAssay Description:Non-competitive inhibition of recombinant human TG2 V224 mutant deamidation activity using Cbz-Gln-Gly as substrate preincubated for 30 mins followed...More data for this Ligand-Target Pair
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assayMore data for this Ligand-Target Pair
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University
Curated by ChEMBL
Stanford University
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair