BDBM50342644 2-((5-methoxy-1H-indol-3-yl)methyl)-6-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline::CHEMBL1770747

SMILES COc1ccc2[nH]cc(CN3CCc4cc(ccc4C3)-c3cccc(c3)C(F)(F)F)c2c1

InChI Key InChIKey=IQURANWCRHYZRE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342644   

TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342644(2-((5-methoxy-1H-indol-3-yl)methyl)-6-(3-(trifluor...)
Affinity DataIC50:  1.03E+5nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed