BDBM50342647 6-(4-(4-methylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline::CHEMBL1770750

SMILES CN1CCN(CC1)c1ccc(cc1C(F)(F)F)-c1ccc2CNCCc2c1

InChI Key InChIKey=XSHJZXZIAWBGCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342647   

TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342647(6-(4-(4-methylpiperazin-1-yl)-3-(trifluoromethyl)p...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342647(6-(4-(4-methylpiperazin-1-yl)-3-(trifluoromethyl)p...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Cav1.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed