BDBM50343992 CHEMBL1779804::N-(2-(5-fluoro-2-(4-fluorophenylthio)benzo[b]thiophen-3-yl)ethyl)acetamide

SMILES CC(=O)NCCc1c(Sc2ccc(F)cc2)sc2ccc(F)cc12

InChI Key InChIKey=QDUMTUZTHHQTAT-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50343992   

TargetMelatonin receptor type 1B(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50343992(CHEMBL1779804 | N-(2-(5-fluoro-2-(4-fluorophenylth...)
Affinity DataKi:  0.870nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50343992(CHEMBL1779804 | N-(2-(5-fluoro-2-(4-fluorophenylth...)
Affinity DataKi:  57nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50343992(CHEMBL1779804 | N-(2-(5-fluoro-2-(4-fluorophenylth...)
Affinity DataEC50:  0.640nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50343992(CHEMBL1779804 | N-(2-(5-fluoro-2-(4-fluorophenylth...)
Affinity DataEC50:  202nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed