BDBM50344305 CHEMBL1779335::rac-6-(2-isopropylpyrazolo[1,5-a]pyridin-3-yl)-5-methyl-4,5-dihydropyridazin-3(2H)-one

SMILES CC(C)c1nn2ccccc2c1C1=NNC(=O)CC1C

InChI Key InChIKey=FBMGIJYUJOIVIO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50344305   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50344305(CHEMBL1779335 | rac-6-(2-isopropylpyrazolo[1,5-a]p...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of human PDE5A catalytic domain using cAMP/cGMP substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50344305(CHEMBL1779335 | rac-6-(2-isopropylpyrazolo[1,5-a]p...)
Affinity DataIC50:  8.90E+4nMAssay Description:Inhibition of human PDE3A catalytic domain using cAMP/cGMP substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50344305(CHEMBL1779335 | rac-6-(2-isopropylpyrazolo[1,5-a]p...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human PDE4B catalytic domain using cAMP/cGMP substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed