BDBM50344321 2-benzyl-6-(2-isopropyl-7-methoxypyrazolo[1,5-a]pyridin-3-yl)-4,5-dihydropyridazin-3(2H)-one::CHEMBL1779439

SMILES COc1cccc2c(c(nn12)C(C)C)C1=NN(Cc2ccccc2)C(=O)CC1

InChI Key InChIKey=XJQUCNLRBNEHNV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50344321   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50344321(2-benzyl-6-(2-isopropyl-7-methoxypyrazolo[1,5-a]py...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of human PDE5A catalytic domain using cAMP/cGMP substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50344321(2-benzyl-6-(2-isopropyl-7-methoxypyrazolo[1,5-a]py...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of human PDE3A catalytic domain using cAMP/cGMP substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50344321(2-benzyl-6-(2-isopropyl-7-methoxypyrazolo[1,5-a]py...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human PDE4B catalytic domain using cAMP/cGMP substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed