BDBM50344396 6-cyclopentyl-2-(phenylethynyl)-7,8-dihydro-1,6-naphthyridin-5(6H)-one::CHEMBL1779869
SMILES O=C1N(CCc2nc(ccc12)C#Cc1ccccc1)C1CCCC1
InChI Key InChIKey=ZDQYIJNPNXCKRM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50344396
Affinity DataKi: 890nMAssay Description:Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrsMore data for this Ligand-Target Pair
Affinity DataEC50: 5.90nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as increase of L-glutamate-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair