BDBM50344630 CHEMBL1779058::N-(4-(4-Fluoro)butyrophenone)-4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ol

SMILES OC12C3C4C5C3C(C3C5CC4C13)N2CCCC(=O)c1ccc(F)cc1

InChI Key InChIKey=HJKLOGARPBXZTP-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50344630   

TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi:  93nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi:  209nMAssay Description:Displacement of [3H]SCH233930 from human D1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi:  1.72E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi:  1.96E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi:  2.37E+3nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi:  2.37E+3nMAssay Description:Binding affinity to Histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH233930 from human D5 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed