BDBM50344807 5-(2,5-dimethylphenyl)-N-(2,6-dimethylphenyl)furan-2-carboxamide::CHEMBL1779911

SMILES Cc1ccc(C)c(c1)-c1ccc(o1)C(=O)Nc1c(C)cccc1C

InChI Key InChIKey=FDAYNZPRBYZBIV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50344807   

TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50344807(5-(2,5-dimethylphenyl)-N-(2,6-dimethylphenyl)furan...)
Affinity DataIC50:  64nMAssay Description:Antagonist activity at S1P4 receptor in human U2OS cells expressing EDG6-linked GAL4-VP16 transcription factor via TEV protease site/beta-arrestin/TE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50344807(5-(2,5-dimethylphenyl)-N-(2,6-dimethylphenyl)furan...)
Affinity DataIC50:  64nMAssay Description:Antagonist activity at human S1P4 receptor expressed in EDG6-bla U2OS cells coexpressing human endothelial differentiation gene 6 linked to GAL4-VP16...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50344807(5-(2,5-dimethylphenyl)-N-(2,6-dimethylphenyl)furan...)
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonist activity at S1P1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50344807(5-(2,5-dimethylphenyl)-N-(2,6-dimethylphenyl)furan...)
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonist activity at S1P5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50344807(5-(2,5-dimethylphenyl)-N-(2,6-dimethylphenyl)furan...)
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonist activity at S1P3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed