BDBM50347681 CHEMBL1802829
SMILES CN(C)S(=O)(=O)Nc1ccc2ccc3ncc(cc3c(=O)c2c1)-c1cnn(C)c1
InChI Key InChIKey=AYNVIPPTDMPZRW-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50347681
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of c-MET (unknown origin) expressed in human GTL16 cells assessed as inhibition of cell proliferationMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of HGF-stimulated c-MET (unknown origin) autophosphorylation at tyrosine 1349 expressed in human GTL16 cells after 2 hrs by Western blotti...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of RON (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of c-MET overexpressed in human GTL-16 cells assessed as phosphorylation at C-terminal Y1349 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant c-Met-catalyzed phosphorylation of N-biotinylated peptide (EQEDEPEGDYFEWLE-CONH2) by time-resolved fluorescence reson...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Kv11.1 channelMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair