BDBM50348732 CHEMBL1801504
SMILES Fc1ccc2c(Cn3c(nc4nccnc34)C3CCC3)cc(=O)[nH]c2c1F
InChI Key InChIKey=ISGGXCWQSOCOCW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50348732
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
Affinity DataEC50: >3.80E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
Affinity DataEC50: >6.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
Affinity DataEC50: 1.65E+4nMAssay Description:Inhibition of human eNOS expressed in HEK293 cells assessed as inhibition A23187 induced nitric oxide production incubated for 24 hrs measured after ...More data for this Ligand-Target Pair
Affinity DataEC50: 430nMAssay Description:Inhibition of mouse iNOS expressed in HEK293 cells assessed as inhibition of nitric oxide production after 18 hrs using 2,3-diaminonaphthalene by flu...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Kalypsys
Curated by ChEMBL
Kalypsys
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of mouse iNOSMore data for this Ligand-Target Pair
Affinity DataEC50: 91nMAssay Description:Inhibition of human iNOS expressed in HEK293 cells assessed as inhibition of nitric oxide production after 18 hrs using 2,3-diaminonaphthalene by flu...More data for this Ligand-Target Pair