BDBM50350110 CHEMBL1814068
SMILES Clc1ccc(NC(=O)c2coc3ccccc3c2=O)cc1
InChI Key InChIKey=JNHOMPJUMGTTSC-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50350110
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Universidade Do Porto
Curated by ChEMBL
Universidade Do Porto
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human MAO-B assessed as inhibition of p-tyramine oxidation to p-hydroxyphenyl-acetaldehyde after 15 mins by fluorimetric methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Universidade Do Porto
Curated by ChEMBL
Universidade Do Porto
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human MAO-BMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Effective concentration for cAMP accumulation relative to alpha-MSH at human MC4RMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Universidade Do Porto
Curated by ChEMBL
Universidade Do Porto
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human microsomal MAO-B expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Universidade Do Porto
Curated by ChEMBL
Universidade Do Porto
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant MAOBMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Universidade Do Porto
Curated by ChEMBL
Universidade Do Porto
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human microsomal MAO-B expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Universidade Do Porto
Curated by ChEMBL
Universidade Do Porto
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate by amplex red-based fluorescence assayMore data for this Ligand-Target Pair