BDBM50350790 BUPIVACAINE HYDROCHLORIDE::Bupivacaine::SAMPL3, G1

SMILES CCCCN1CCCCC1C(=O)Nc1c(C)cccc1C

InChI Key InChIKey=LEBVLXFERQHONN-UHFFFAOYSA-N

Data  10 IC50  1 EC50  1 ITC

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50350790   

TargetPotassium channel subfamily K member 2(Homo sapiens (Human))
Korea Institute of Science and Technology

LigandPNGBDBM50350790(BUPIVACAINE HYDROCHLORIDE | Bupivacaine | SAMPL3, ...)
Affinity DataEC50:  1.13E+5nMpH: 7.3 T: 2°CAssay Description:The hTREK1 stable cell lines were seeded at a density of 10 000 cells/well in a 12-well plate. Whole-cell membrane currents were amplified using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 50350790   

HostPNGBDBM197280(SAMPL3, H1)
University of California San Diego

GuestPNGBDBM50350790(BUPIVACAINE HYDROCHLORIDE | Bupivacaine | SAMPL3, ...)
ITC DataΔG°: -5.85kcal/mole logk: 1.80E+4
pH: 7.4 T: 24.85°C 
Cell InfoPC cidPC sid