BDBM50352058 CHEMBL560241
SMILES Cc1cc(n[nH]1)-c1ccc(Cl)c(c1)C(=O)NCC1(O)CCCCCC1
InChI Key InChIKey=INFAZCALLSRXIC-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50352058
Affinity DataIC50: 3nMAssay Description:Antagonist activity at P2X7R expressed in HEK293 cells assessed as inhibition of ATP-induced YO-PRO-1 uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as effect on BzATP-induced Yo-Pro uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Antagonist activity at P2X7R expressed in LPS-activated human monocytes assessed as inhibition of ATP-induced IL-1beta release in presence of low ser...More data for this Ligand-Target Pair
Affinity DataIC50: 121nMAssay Description:Antagonist activity at P2X7R expressed in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL-1beta releaseMore data for this Ligand-Target Pair