BDBM50355002 CHEMBL1834954

SMILES OC(=O)c1cc(ccc1O)C#Cc1ccc(cc1)S(=O)(=O)Nc1ccccn1

InChI Key InChIKey=JJNQWYPLIWCKRB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50355002   

TargetCystine/glutamate transporter(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50355002(CHEMBL1834954)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of xCT-mediated cystein/glutamate transporter (unknown origin) assessed as reduction in L-[14C]cyctein uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystine/glutamate transporter(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50355002(CHEMBL1834954)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed