BDBM50355936 CHEMBL1910411

SMILES CN(C)[C@H]1C[C@H](Nc2ccc(cc12)[N+]([O-])=O)C(C)(C)CO

InChI Key InChIKey=YNYAUBNZRZVNLX-KBPBESRZSA-N

Data  7 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50355936   

TargetMineralocorticoid receptor(RAT)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355936(CHEMBL1910411)
Affinity DataIC50:  1.40E+4nMAssay Description:Displacement of [3H]Aldo from mineralocorticoid receptor in Sprague-Dawley rat kidney after 2 hrs by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355936(CHEMBL1910411)
Affinity DataIC50:  45nMAssay Description:Displacement of [3H]testosterone from androgen receptor in Sprague-Dawley rat prostate gland after 2 hrs by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355936(CHEMBL1910411)
Affinity DataIC50:  26nMAssay Description:Competitive binding affinity to rat androgen receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355936(CHEMBL1910411)
Affinity DataEC50:  13nMAssay Description:Agonist activity at rat androgen receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355936(CHEMBL1910411)
Affinity DataEC50:  13nMAssay Description:Agonist activity at rat Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProgesterone receptor(Oryctolagus cuniculus)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355936(CHEMBL1910411)
Affinity DataIC50:  3.40E+3nMAssay Description:Displacement of [3H]progesterone from progesterone receptor in JW rabbit uterus after 2 hrs by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355936(CHEMBL1910411)
Affinity DataIC50:  4.90E+4nMAssay Description:Displacement of [3H]Dex from glucocorticoid receptor in Sprague-Dawley rat liver after 2 hrs by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355936(CHEMBL1910411)
Affinity DataIC50:  26nMAssay Description:Binding affinity to rat Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355936(CHEMBL1910411)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]E2 from estrogen receptor in JW rabbit uterus after 2 hrs by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed