BDBM50356427 CHEMBL1911559

SMILES Fc1cccc(Cl)c1Cn1cc(C(=O)Nc2ccc(cc2)N2CCOCC2)c(=O)c2[nH]c(=O)ccc12

InChI Key InChIKey=MSQQXQFZLXSONK-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50356427   

TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Biocrea

Curated by ChEMBL
LigandPNGBDBM50356427(CHEMBL1911559)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant PDE11AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Biocrea

Curated by ChEMBL
LigandPNGBDBM50356427(CHEMBL1911559)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant PDE5AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356427(CHEMBL1911559)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant PDE1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Biocrea

Curated by ChEMBL
LigandPNGBDBM50356427(CHEMBL1911559)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant PDE2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Biocrea

Curated by ChEMBL
LigandPNGBDBM50356427(CHEMBL1911559)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant PDE4A4 expressed in baculovirus infected insect Sf21 cells after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356427(CHEMBL1911559)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant PDE8AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Biocrea

Curated by ChEMBL
LigandPNGBDBM50356427(CHEMBL1911559)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant PDE9AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Biocrea

Curated by ChEMBL
LigandPNGBDBM50356427(CHEMBL1911559)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant PDE10AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Biocrea

Curated by ChEMBL
LigandPNGBDBM50356427(CHEMBL1911559)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant PDE7A1 expressed in baculovirus infected insect Sf21 cells after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Biocrea

Curated by ChEMBL
LigandPNGBDBM50356427(CHEMBL1911559)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant PDE3AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed