BDBM50357677 CHEMBL1914951

SMILES CC(C)(C)Nc1c(nc2ccccn12)-c1ccc(cc1)C(O)=O

InChI Key InChIKey=IUOQJYAQYVEYIT-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357677   

TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50357677(CHEMBL1914951)
Affinity DataKi:  7.50E+4nMAssay Description:Competitive inhibition of human topoisomerase-2 alpha-ATPase activity by Lineweaver-Burk assay in presence of 200 to 520 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute Of Pharmaceutical Education And Research (Niper)

Curated by ChEMBL
LigandPNGBDBM50357677(CHEMBL1914951)
Affinity DataIC50:  5.27E+4nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated decatenation of kDNA by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed