BDBM50358220 CHEMBL455389

SMILES CC[C@H](CO)Nc1nc(NCc2cccnc2)c2ncn(C(C)C)c2n1

InChI Key InChIKey=ITWHOUBMQIJNKR-CQSZACIVSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50358220   

TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358220(CHEMBL455389)
Affinity DataIC50:  180nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358220(CHEMBL455389)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of ERK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Sus scrofa)
Universite Paris-Descartes

Curated by ChEMBL
LigandPNGBDBM50358220(CHEMBL455389)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of pig brain GSK3alpha/betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50358220(CHEMBL455389)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at N-type Cav2.2 channel expressed in tsA201 cell assessed as calcium current by whole-cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358220(CHEMBL455389)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed