BDBM50358936 CHEMBL1923705

SMILES C[C@H](NC(=O)c1cc(cc(c1)-c1nc(c[nH]1)-c1cccc(F)c1)N(C)S(C)(=O)=O)c1ccccc1

InChI Key InChIKey=CIWFAULALHGEOR-KRWDZBQOSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50358936   

TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50358936(CHEMBL1923705)
Affinity DataKi:  180nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50358936(CHEMBL1923705)
Affinity DataKi:  1.82E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50358936(CHEMBL1923705)
Affinity DataIC50:  187nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by FRET analysisChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
University Of Sharjah

Curated by ChEMBL
LigandPNGBDBM50358936(CHEMBL1923705)
Affinity DataIC50:  1.87E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by FRET analysisChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed