BDBM50359152 CHEMBL1922972

SMILES Cn1cc(C=c2c(=O)[nH][nH]\c2=c2/snnc2=C)c2c(OCc3c(F)cccc3Cl)cccc12

InChI Key InChIKey=PZPRNRYGJJTJJT-LAEBEENCSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50359152   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50359152(CHEMBL1922972)
Affinity DataIC50:  200nMAssay Description:Inhibition of nucleophosmin-fused ALK autophosphorylation in human Karpas299 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50359152(CHEMBL1922972)
Affinity DataIC50:  21nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50359152(CHEMBL1922972)
Affinity DataIC50:  720nMAssay Description:Inhibition of GST-tagged intracellular domain of IR by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed