BDBM50359546 CHEMBL1927270

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCCNC(=O)C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O

InChI Key InChIKey=XGFIVOHFTMYGLC-JZVHMONDSA-N

Data  6 KI  8 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50359546   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataKi:  0.560nMAssay Description:Displacement of [3H]DAMGO from recombinant human mu opioid receptor expressed in CHO cell membranes after 120 mins by liquid scintillation counter an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]U-69593 from recombinant human kappa opioid receptor expressed in CHO cell membranes after 120 mins by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataKi:  171nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataKi:  279nMAssay Description:Displacement of [3H]deltorphin-2 from recombinant human delta opioid receptor expressed in CHO cell membranes after 120 mins by liquid scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataIC50:  279nMAssay Description:Displacement of [3H][Ile5,6]deltorphin 2 from delta opioid receptor in Wistar rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human recombinant MOP expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataIC50:  279nMAssay Description:Inhibition of Wistar rat brain membrane DOPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataIC50:  0.560nMAssay Description:Displacement of [3H]DAMGO from Wistar rat mu opioid receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataEC50:  6.60nMAssay Description:Agonist activity at human recombinant KOR expressed in CHO cells assessed as calcium mobilization by Fluo-4 AM based fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human recombinant MOR expressed in CHO cells assessed as calcium mobilization by Fluo-4 AM based fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of Wistar rat brain membrane KOPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataIC50:  279nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataIC50:  0.560nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed