BDBM50361254 CHEMBL1934896

SMILES Cc1ccc(NC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)NO)cc1C

InChI Key InChIKey=FDDOLFDMTDIZNX-UHFFFAOYSA-N

Data  6 KI  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50361254   

TargetHistone deacetylase 7(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibitory potency against Varicella zoster virus ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of human HDAC1 using Boc-Lys(Ac)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by trypsi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi:  8.40E+3nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatum by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibitory potency against Varicella zoster virus ribonucleotide reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi: >5.00E+4nMAssay Description:Compound was tested for its ability to inhibit the binding to recombinant human Selectin E immobilized on SPA beads of radiolabeled HL60 cell membran...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKd:  1.40E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKd:  2.40E+4nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-L-Lys(acetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKd:  8.80E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-L-Lys(acetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase-like amidohydrolase(Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)
University Of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKd:  260nMAssay Description:Inhibition of Bordetella FB188 HDAH using Boc-L-Lys(acetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
University Of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKd:  3.30E+3nMAssay Description:Inhibition of recombinant human HDAC7 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed