BDBM50363655 CHEMBL1945236
SMILES NC(=N)c1ccc(\C=C2\N=C(OC2=O)c2ccccc2)cc1
InChI Key InChIKey=JBHISGPWLXASFE-GXDHUFHOSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50363655
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant tPA using H-D-Ile-Pro-Arg-pNA.2HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins by sp...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human plasma thrombin using pyroGlu-Pro-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp
Curated by ChEMBL
University Of Antwerp
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human uPA using pyroGlu-Gly-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins by spectrop...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human plasma plasmin using pyroGlu-Pro-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of human plasma plasmin using pyroGlu-Pro-Arg-pNA-HCl as substrate measured for 5 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.47E+3nMAssay Description:Inhibition of purified human factor 10a using Suc-Ile-Glu(gammaPip)-GlyArg-pNa-HCl as substrate measured for 5 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of human plasma kallikrein using D-Pro-Phe-Arg-pNA-2HCl as substrate measured for 5 mins by spectrophotometric assayMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Antwerp
Curated by ChEMBL
University Of Antwerp
Curated by ChEMBL
Affinity DataIC50: 8.67E+3nMAssay Description:Inhibition of human uPA using pyro-Glu-Gly-Arg-pNA as substrate assessed as para-nitroaniline release from substrate measured for 5 mins by spectroph...More data for this Ligand-Target Pair
Affinity DataIC50: 6.85E+4nMAssay Description:Inhibition of recombinant human tPA using H-D-Ile-Pro-L-Arg-pNA-2HCl as substrate measured for 5 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.61E+4nMAssay Description:Inhibition of human plasma thrombin using pyroGlu-Pro-Arg-pNA-HCl as substrate measured for 5 mins by spectrophotometric assayMore data for this Ligand-Target Pair