BDBM50364141 CHEMBL1951415

SMILES Nc1nccc(n1)-c1c(ncn1C1CCCCC1)-c1ccc(F)cc1

InChI Key InChIKey=WUDBUIUHVNECTM-UHFFFAOYSA-N

Data  18 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50364141   

TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50364141(CHEMBL1951415)
Affinity DataIC50:  8nMAssay Description:Inhibition of human CK1epsilon expressed in Escherichia coli BL21 using PLSRTLpSVASLPGL as substrate after 3 hrs by KinaseGlo assayMore data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50364141(CHEMBL1951415)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant CK1delta expressed in Escherichia coli using PLSRTLpSVASLPGL as substrate after 2 hrs by KinaseGlo assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50364141(CHEMBL1951415)
Affinity DataIC50:  150nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50364141(CHEMBL1951415)
Affinity DataIC50:  190nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50364141(CHEMBL1951415)
Affinity DataIC50:  13nMAssay Description:Inhibition of Casein kinase 1 deltaMore data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50364141(CHEMBL1951415)
Affinity DataIC50:  80nMAssay Description:Inhibition of Casein kinase 1 epsilonMore data for this Ligand-Target Pair