BDBM50364773 CHEMBL1952134

SMILES CN(C)c1cccc(c1)-n1nnc2ccc(NCC3CCNCC3)nc12

InChI Key InChIKey=NFMGQYVXXDIVFX-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50364773   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50364773(CHEMBL1952134)
Affinity DataEC50:  140nMAssay Description:Inhibition of human PIM1 expressed in H1299 cells assessed as inhibition of BAD phosphorylation at S112 in absense of serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50364773(CHEMBL1952134)
Affinity DataIC50:  5nMAssay Description:Inhibition of PIM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50364773(CHEMBL1952134)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant PIM1 in presence of ATP by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50364773(CHEMBL1952134)
Affinity DataIC50:  11nMAssay Description:Inhibition of PIM3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50364773(CHEMBL1952134)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50364773(CHEMBL1952134)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PIM2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed