BDBM50366558 ONAPRISTONE::ZK-98299
SMILES CN(C)c1ccc(cc1)[C@H]1C[C@]2(C)[C@@H](CC[C@]2(O)CCCO)[C@@H]2CCC3=CC(=O)CCC3=C12
InChI Key InChIKey=IEXUMDBQLIVNHZ-YOUGDJEHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 26 hits for monomerid = 50366558
Affinity DataKi: 18nMAssay Description:Antagonist activity against human progesterone receptor (hPR) using cotransfection assay in CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Binding affinity against Baculovirus-Expressed hPR-AMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Binding affinity at human progesterone receptor.More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Binding affinity determined for human Progesterone receptor A isoformMore data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Binding affinity was determined for human glucocorticoid receptor(hGR).More data for this Ligand-Target Pair
Affinity DataKi: >100nMAssay Description:Binding affinity for human Androgen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Binding affinity against human progesterone receptor (hPR) in a competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Cross-reactivity as binding to human glucocorticoid receptor (hGR)More data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Antagonist activity against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
Affinity DataIC50: 269nMAssay Description:Inhibition of antagonist activity towards Androgen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:Inhibition of antagonist activity towards mineralocorticoid receptor (hMR)More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of antagonist activity towards glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against human glucocorticoid receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 269nMAssay Description:Inhibitory activity against human Androgen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against human mineralocorticoid receptor (hMR)More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Antagonistic potency to the human progesterone receptor measured in the T-47D alkaline phosphatase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.20nMAssay Description:Antagonistic activity at human progesterone receptor in CV-1 cells.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Cross-reactivity as binding to human mineralocorticoid receptor (hMR)More data for this Ligand-Target Pair
Affinity DataIC50: 269nMAssay Description:Cross-reactivity as binding to human androgen receptor (hAR)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity against human progesterone receptor (hPR) in a competitive binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Antagonist activity against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:In vitro antagonist activity against human progesterone receptor isoform B(hPR-B) in mammalian(CV-1) cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human progesterone receptor activation in T47D human breast cancer cell.More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity against human progesterone receptor (hPR) using cotransfection assay in CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Concentration required to give half-maximal inhibition against human Progesterone receptor B isoform in co-transfected CV-1 cell lines.More data for this Ligand-Target Pair