BDBM50366670 CHEMBL4173488

SMILES COc1cc2c(cc1-c1c(C)noc1C)[nH]c1nc(C)nc(Nc3cc(nn3C)C3CC3)c21

InChI Key InChIKey=JIYPVUCBRQNICX-UHFFFAOYSA-N

Data  1 KI  2 IC50  34 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50366670   

TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human PLK4 using casein as substrate in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataIC50:  2nMAssay Description:Inhibition of FAM-labeled ZBA248 binding to recombinant human BRD4 bromodomain 1 (44 to 168 residues) expressed in Rosetta2 Escherichia coli DE3 cell...More data for this Ligand-Target Pair