BDBM50366855 CHEMBL525803::Chloropeptin

SMILES CN1[C@@H](Cc2ccc(Oc3cc4cc(c3O)-c3cccc5c(C[C@@H](NC(=O)C(=O)c6cc(Cl)c(O)c(Cl)c6)C(=O)N[C@H](c6cc(Cl)c(O)c(Cl)c6)C(=O)N[C@H]4C(=O)N[C@H](c4cc(Cl)c(O)c(Cl)c4)C1=O)c[nH]c35)cc2)C(=O)N[C@@H](C(O)=O)c1ccc(O)cc1

InChI Key InChIKey=FRRCHJPQSWYJSH-OZICGBTHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50366855   

TargetT-cell surface glycoprotein CD4(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50366855(CHEMBL525803 | Chloropeptin)
Affinity DataIC50:  130nMAssay Description:Inhibitory concentration against CD4-gp120 binding in the absence of fetal bovine serum (FBS); Range is 0.13-0.5 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50366855(CHEMBL525803 | Chloropeptin)
Affinity DataIC50:  300nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 FabI in the presence of NADH using crotonyl CoA as substrate by measuring NADH consumption rateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366855(CHEMBL525803 | Chloropeptin)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366855(CHEMBL525803 | Chloropeptin)
Affinity DataIC50:  400nMAssay Description:Inhibition of HIV1 integrase 3' processing/strand transfer coupled activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed