BDBM50370597 CHEMBL4174189::US10954217, Example 00231

SMILES CCOC(=O)CCN1CCN(CC1)c1ccc2CN(Cc2c1)C(=O)OCc1ccccc1

InChI Key InChIKey=VPVXEPWFTGBGGT-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50370597   

TargetSigma intracellular receptor 2(Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM50370597(CHEMBL4174189 | US10954217, Example 00231)
Affinity DataKi:  134nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370597(CHEMBL4174189 | US10954217, Example 00231)
Affinity DataKi:  134nMAssay Description:Displacement of [3H]-ditolylguanidine from sigma2 receptor in rat PC12 cells by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370597(CHEMBL4174189 | US10954217, Example 00231)
Affinity DataKi:  352nMAssay Description:Displacement of [3H]-Pentazocine from sigma1 receptor in guinea pig brain membrane by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM50370597(CHEMBL4174189 | US10954217, Example 00231)
Affinity DataKi:  352nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H3 receptor(Homo sapiens (Human))
University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370597(CHEMBL4174189 | US10954217, Example 00231)
Affinity DataKi:  357nMAssay Description:Displacement of [3H]-alpha-methylhistamine from human histamine H3 receptor expressed in HEK Flp-In cells after 90 mins by microbeta scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370597(CHEMBL4174189 | US10954217, Example 00231)
Affinity DataKi:  1.06E+3nMAssay Description:Displacement of [3H]-Pyrilamine from human histamine H1 receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370597(CHEMBL4174189 | US10954217, Example 00231)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]-iodoaminopotentidine from human histamine H2 receptor expressed in stable HEK cells after 90 mins by microbeta scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370597(CHEMBL4174189 | US10954217, Example 00231)
Affinity DataKi:  1.31E+3nMAssay Description:Displacement of [3H]-Nisoxetine from human NET receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370597(CHEMBL4174189 | US10954217, Example 00231)
Affinity DataKi:  2.47E+3nMAssay Description:Displacement of [3H]-QNB/[3H]-NMS from human muscarinic M1 receptor expressed in stable CHO cells after 90 mins by microbeta scintillation counting m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed